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Invitrogen™ SEMA7A Monoclonal Antibody (MEM-150)
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Catalog No. 01675967
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100 μg
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Catalog No. Quantity
01-675-967 100 μg
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Catalog No. 01-675-967 Supplier Invitrogen™ Supplier No. MA119203
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Description

Mouse Monoclonal Antibody

This antibody reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes. Western Blot: non-reducing conditions.

CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
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Specifications

Antigen SEMA7A
Applications Flow Cytometry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone MEM-150
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 15mM sodium azide; pH 8
Gene SEMA7A
Gene Accession No. O75326
Gene Alias 2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1
Gene Symbols SEMA7A
Host Species Mouse
Immunogen T cell line HPB-ALL.
Purification Method Sequential chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8482
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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