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Invitrogen™ SEMA7A Polyclonal Antibody
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Catalog No. PIPA588314
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100 μL
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PIPA588314 100 μL
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Catalog No. PIPA588314 Supplier Invitrogen™ Supplier No. PA588314
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Rabbit Polyclonal Antibody

Immunogen sequence: QGHLRSGPRI FAVWKGHVGQ DRVDFGQTEP HTVLFHEPGS SSVWVGGRGK VYLFDFPEGK NASVRTVNIG STKGSCLDKR DCENYITLLE RRSEGLLACG TNARHPSCWN LVNGTVVPLG EMRGYAPFSP DENSLVLFEG DEVYSTIRKQ EYNGKIPRFR RIRGESELYT SDTVMQNPQF IKATIVHQDQ AYDDKIYYFF REDNPDKNPE APLNVSRVAQ LCRGDQGGES SLSVSK; Positive Samples: A549, HT-29, Raji; Cellular Location: Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor.

CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA7A
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SEMA7A
Gene Accession No. O75326
Gene Alias 2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1
Gene Symbols SEMA7A
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 45-280 of human SEMA7A (NP_0036031).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8482
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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