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Tocris Bioscience™ Senexin A Available on GSA/VA Contract for Federal Government customers only.

Cdk8 inhibitor

Manufacturer:  Tocris Bioscience™ 4875/10

Catalog No. 48-751-0


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Description

Description

Cyclin-dependent kinase 8 (cdk8) inhibitor (IC50 = 280 nM). Also binds to cdk19 in an ATP-competitive manner. Inhibits p21-induced transcription. Reverses doxorubicin -induced tumor-promoting paracrine activities in vivo.

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