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Invitrogen™ SENP5 Polyclonal Antibody
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Catalog No. 01675593
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100 μg
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Catalog No. Quantity
01-675-593 100 μg
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Catalog No. 01-675-593 Supplier Invitrogen™ Supplier No. PA141239
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Description

Rabbit Polyclonal Antibody

Suggested positive control: HeLa or NIH-3T3 whole cell lysate. Immunogen sequence: CNRKPFINRE ITNYRARH.

SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the 'GG' region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SENP5
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene SENP5
Gene Accession No. Q6NXL6, Q96HI0
Gene Alias 6230429P13Rik; A730063F07Rik; AI851888; BB189556; DKFZp564O1016; FKSG45; FLJ42398; MGC27076; Senp5; sentrin/SUMO-specific protease SENP5; Sentrin-specific protease 5; SMT3IP3; SUMO/sentrin specific peptidase 5; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5
Gene Symbols SENP5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 229-246 of human SENP5.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 205564, 320213
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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