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Invitrogen™ SENP5 Polyclonal Antibody
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Catalog No. PIPA575185
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100 μL
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PIPA575185 100 μL
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Catalog No. PIPA575185 Supplier Invitrogen™ Supplier No. PA575185
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the GG region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SENP5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SENP5
Gene Accession No. Q6NXL6, Q96HI0
Gene Alias 6230429P13Rik; A730063F07Rik; AI851888; BB189556; DKFZp564O1016; FKSG45; FLJ42398; MGC27076; Senp5; sentrin/SUMO-specific protease SENP5; Sentrin-specific protease 5; SMT3IP3; SUMO/sentrin specific peptidase 5; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5
Gene Symbols SENP5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 650-697 of Human SENP5.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 205564, 303874, 320213
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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