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Invitrogen™ SENP5 Polyclonal Antibody
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Catalog No. PIPA5104468
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PIPA5104468 100 μL
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Catalog No. PIPA5104468 Supplier Invitrogen™ Supplier No. PA5104468
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SENP5.

SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the GG region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SENP5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SENP5
Gene Accession No. Q6NXL6, Q96HI0
Gene Alias 6230429P13Rik; A730063F07Rik; AI851888; BB189556; DKFZp564O1016; FKSG45; FLJ42398; MGC27076; Senp5; sentrin/SUMO-specific protease SENP5; Sentrin-specific protease 5; SMT3IP3; SUMO/sentrin specific peptidase 5; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5
Gene Symbols SENP5
Host Species Rabbit
Immunogen A synthesized peptide derived from human SENP5(Accession Q96HI0), corresponding to amino acid residues F661-S711.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 205564, 320213
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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