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SENP8 Mouse anti-Human, Clone: OTI3E4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF804753

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Principal Names: Cysteine protease FKSG8; DEN1; FKSG8; HsT17512; NEDP1; PRSC2; SUMO/sentrin specific protease family member 8; Official Gene Symbol: SENP8 Gene ID: 123228 (Human) Gene Map Locus: 15q23 (Human) SENP8, is a novel cysteine protease which belongs to the ULP family of deubiquitinases. ULP family members consist of a C-terminal core catalytic domain and N-terminal extensions determining substrate specificity. SENP8, a 24KDa protein, plays a major role in regulating NEDD8 pathway. It processes preNEDD8 to its mature form and deconjugates NEDD8 from substrates such as Cullins and p53. SENP8 may play a role in preventing accumulation of hyper-neddylated cullin and maintaining the level of mono-neddylated cullin that is thought to increase the efficiency of ubiquitination by SCF ubiquitin ligases.Specifications
SENP8 | |
Monoclonal | |
Unconjugated | |
SENP8 | |
DEN1, NEDP1, PRSC2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
123228 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI3E4 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q96LD8 | |
SENP8 | |
Full length human recombit protein of human SENP8 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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