Invitrogen™ SEP15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA569531

Catalog No. PIPA569531

Description

This target displays homology in the following species: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%; Zebrafish: 100%.

The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: SEP15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Selenof
• Gene Alias: 15 kDa selenoprotein; 15 kDa selenoprotein isoform 1 precursor; 15 kDa selenoprotein SeP15; 15kDa selenoprotein; 15-kDa selenoprotein; 15-Sep; 9430015P09Rik; cb29; Selenof; selenoprotein; selenoprotein 15; selenoprotein F; Sep15; sep15 protein; si:dkey-43b14.10; zgc:86882
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113922
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q923V8
• Gene Symbols: Selenof
• Immunogen: synthetic peptide directed towards the C-terminal region of rat SEP15.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov