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Invitrogen™ SEP15 Polyclonal Antibody
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Catalog No. PIPA5103009
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PIPA5103009 100 μL
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Catalog No. PIPA5103009 Supplier Invitrogen™ Supplier No. PA5103009
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SEP15.

The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEP15
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Selenof
Gene Accession No. O60613, Q923V8
Gene Alias 15 kDa selenoprotein; 15 kDa selenoprotein isoform 1 precursor; 15 kDa selenoprotein SeP15; 15kDa selenoprotein; 15-kDa selenoprotein; 15-Sep; 9430015P09Rik; cb29; Selenof; selenoprotein; selenoprotein 15; selenoprotein F; Sep15; sep15 protein; si:dkey-43b14.10; zgc:86882
Gene Symbols Selenof
Host Species Rabbit
Immunogen A synthesized peptide derived from human SELENOF(Accession O60613), corresponding to amino acid residues E35-L63.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113922, 9403
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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