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Tocris Bioscience™ Sephin 1
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Catalog No. 555350
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555350 50 mg
555310 10 mg
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Catalog No. 555350 Supplier Tocris Bioscience™ Supplier No. 5553/50
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Description

Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1

Sephin 1 is an inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1. Does not bind PPP1R15B or have α2 adrenergic agonist activity. Cytoprotective in endoplasmic reticulum stressed cells in vitro. Prevents defects associated with protein misfolding in a mouse Charcot-Marie Tooth-1B model. Orally available.

Specifications

Chemical Name or Material (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt
Quantity 50 mg
Target Protein Ser/Thr Phosphatase Inhibitors
Molecular Formula C8H9ClN4.CH2O3
Formula Weight 258.66
Purity >98%
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