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Invitrogen™ SEPN1 Polyclonal Antibody
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Catalog No. PA550752
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100 μL
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PA550752 100 μL
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Catalog No. PA550752 Supplier Invitrogen™ Supplier No. PA550752
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total SEPN1 protein.

SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEPN1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene SELENON
Gene Accession No. Q9NZV5
Gene Alias 1110019I12Rik; AI414492; cb686; CFTD; FLJ24021; MDRS1; RSMD1; RSS; selenon; Selenoprotein N; selenoprotein N, 1; SELN; SePN; sepn1; wu:fb06g01; wu:fb73d02; wu:fv41b08; zgc:101091
Gene Symbols SELENON
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human selenoprotein N, 1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57190
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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