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Invitrogen™ SEPN1 Polyclonal Antibody
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Catalog No. PIPA569493
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100 μL
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PIPA569493 100 μL
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Catalog No. PIPA569493 Supplier Invitrogen™ Supplier No. PA569493
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rat: 86%.

SEPN1 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Mutations in SEPN1 gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEPN1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SELENON
Gene Accession No. D3Z2R5
Gene Alias 1110019I12Rik; AI414492; cb686; CFTD; FLJ24021; MDRS1; RSMD1; RSS; selenon; Selenoprotein N; selenoprotein N, 1; SELN; SePN; sepn1; wu:fb06g01; wu:fb73d02; wu:fv41b08; zgc:101091
Gene Symbols SELENON
Host Species Rabbit
Immunogen synthetic peptide corresponding to a region of mouse SEPN1 (aa 501-550).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74777
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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