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Invitrogen™ SEPT2 Polyclonal Antibody
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Catalog No. PIPA5118255
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100 μL
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PIPA5118255 100 μL
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Catalog No. PIPA5118255 Supplier Invitrogen™ Supplier No. PA5118255
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Rabbit Polyclonal Antibody

SEPT2 Polyclonal Antibody for Western Blot, IP

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEPT2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.03% ProClin 300; pH 7
Gene SEPTIN2
Gene Accession No. Q15019
Gene Alias 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11
Gene Symbols SEPTIN2
Host Species Rabbit
Immunogen E. coli-derived Human SEPT2 fragment.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4735
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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