SEPT4 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 124761AP150UL

Catalog No. 50-172-8007

Description

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

Specifications

• Antigen: SEPT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEPT4
• Gene Alias: ARTS, BRADEION, Bradeion beta, Brain protein H5, CE5B3, CE5B3 beta, Cerebral protein 7, H5, hCDCREL 2, hucep 7, MART, Peanut like protein 2, PNUTL2, SEP4, SEPT4, septin 4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5414
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43236
• Gene Symbols: SEPT4
• Immunogen: SEPT4 Fusion Protein Ag3185
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG