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Invitrogen™ SEPT5 Polyclonal Antibody
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Catalog No. PIPA584621
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PIPA584621 100 μL
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Catalog No. PIPA584621 Supplier Invitrogen™ Supplier No. PA584621
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Rabbit Polyclonal Antibody

Immunogen sequence: VPLIAKADCL VPSEIRKLKE RIREEIDKFG IHVYQFPE Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEPT5
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SEPTIN5
Gene Accession No. Q99719
Gene Alias 5-Sep; CDCREL; CDCREL1; CDCREL-1; CDCrel-1A; cell division control related protein 1; cell division control-related protein 1; H5; HCDCREL-1; peanut-like 1; peanut-like 1 homolog; peanut-like protein 1; platelet glycoprotein Ib beta chain; Pnutl1; Sept5; septin 5; SEPTIN5; septin-5
Gene Symbols SEPTIN5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SEPT5. Recombinant protein control fragment (Product #RP-103688).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5413
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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