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Invitrogen™ SEPT5 Recombinant Mouse Monoclonal Antibody (SP18)
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Catalog No. PIMA547887
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200 μg
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PIMA547887 200 μg
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Catalog No. PIMA547887 Supplier Invitrogen™ Supplier No. MA547887
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Description

Mouse Recombinant Monoclonal Antibody

Specificity: This antibody recognises CDCrel-1 and does not cross-react with CDCrel-2.

This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEPT5
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Recombinant Monoclonal
Clone SP18
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene SEPTIN5
Gene Accession No. Q99719, Q9JJM9
Gene Alias 5-Sep; CDCREL; CDCREL1; CDCREL-1; CDCrel-1A; cell division control related protein 1; cell division control-related protein 1; H5; HCDCREL-1; peanut-like 1; peanut-like 1 homolog; peanut-like protein 1; platelet glycoprotein Ib beta chain; Pnutl1; Sept5; septin 5; SEPTIN5; septin-5
Gene Symbols SEPTIN5
Host Species Mouse
Immunogen Immunoprecipitate from human brain.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116728, 5413
Target Species Human, Rat, Rabbit
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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