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Septin 2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501567135
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20 μL; Unconjugated
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Catalog No.
50-156-7135 20 μL; Unconjugated
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Catalog No. 50-156-7135 Supplier Bethyl Laboratories, Inc Supplier No. A304210AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Orangutan

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Specifications

Antigen Septin 2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SEPT2
Gene Accession No. P42208, Q15019
Gene Alias SEPT2; septin 2; DIFF6; KIAA0158; NEDD5; Pnutl3; hNedd5; neural precursor cell expressed, developmentally down-regulated 5
Gene Symbols Sept2
Host Species Rabbit
Immunogen Between 275 and 325
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18000, 4735
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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