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Invitrogen™ SERCA1 ATPase Recombinant Rabbit Monoclonal Antibody (2T8S3)
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Catalog No. PIMA537935
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100 μL
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PIMA537935 100 μL
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Catalog No. PIMA537935 Supplier Invitrogen™ Supplier No. MA537935
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Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse skeletal muscle Immunogen sequence: ALSVLVTIEM CNALNSLSEN QSLLRMPPWV NIWLLGSICL SMSLHFLILY VDPLPMIFKL RALDLTQWLM VLKISLPVIG LDEILKFVAR NYLEDPEDER RK.

ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERCA1 ATPase
Applications ELISA, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 2T8S3
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ATP2A1
Gene Accession No. Q64578, Q8R429
Gene Alias adult Ca2+ ATPase; ATP2A; ATP2A1; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; ATPase, Ca++ transporting, ubiquitous; Ca2+ ATPase; calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; neonatal Ca2+ ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA; SERCA ATPase; Serca1; SERCA1a; SR Ca(2+)-ATPase 1
Gene Symbols ATP2A1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 900-1001 of human SERCA1/ATP2A1 (O14983).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116601, 11937
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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