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SERPINA1 Mouse anti-Canine, Human, Clone: OTI5B12, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF500371

Encompass_Preferred

Catalog No. 50-165-9450


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
Specifications

Specifications

SERPINA1
Monoclonal
Unconjugated
SERPINA1
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF
Mouse
Affinity Chromatography
RUO
480422, 5265
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
OTI5B12
PBS with 8% trehalose and no preservative; pH 7.3
P01009
SERPINA1
Full length human recombit protein of human SERPINA1 produced in HEK293T cell.
100 μg
Primary
Canine, Human
Antibody
IgG1
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