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Invitrogen™ SERPINA3 Polyclonal Antibody
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Catalog No. PIPA546907
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100 μg
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PIPA546907 100 μg
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Catalog No. PIPA546907 Supplier Invitrogen™ Supplier No. PA546907
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse (rm) Serpin A1 is observed, and less than 3% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3N, rhSerpin A4, rhSerpin A5, rhSerpin A9, rhSerpin C1, rhSerpin F2, and rhSerpin F1/PEDF is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINA3
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SERPINA3
Gene Accession No. P01011
Gene Alias AACT; ACT; alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin His-Pro-less; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3; serpin family A member 3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; SERPINA3
Gene Symbols SERPINA3
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Serpin A3/alpha 1-Antichymotrypsin Asn26-Ala423.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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