Invitrogen™ SERPINA5 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547109

Catalog No. PIPA547109

Description

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3, rhSerpin A4, recombinant mouse (rm) Serpin A5, rhSerpin C1, rmSerpin D1, and rhSerpin F2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SERPINA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINA5
• Gene Alias: 4933415L04; acrosomal serine protease inhibitor; alpha-1 antiproteinase; antitr; antitrypsin; LOC480424; LOC483954; PAI3; PAI-3; Pci; PCI-B; PLANH3; Plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor III; plasminogen activator inhibitor-3; PROCI; Protein C inhibitor; serine (or cysteine) peptidase inhibitor, clade A, member 5; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serine (or cysteine) proteinase inhibitor, clade A, member 5; serpin A5; serpin B3; serpin family A member 5; serpin family B member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serpin peptidase inhibitor, clade A, member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINA5; SERPINB3; SERPINB4
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5104
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P05154
• Gene Symbols: SERPINA5
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Serpin A5/Protein C Inhibitor His20-Pro406.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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