Invitrogen™ SERPINA5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578101

Catalog No. PIPA578101

Description

Positive Control: HepG2 conditioned medium Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SERPINA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINA5
• Gene Alias: 4933415L04; acrosomal serine protease inhibitor; alpha-1 antiproteinase; antitr; antitrypsin; LOC480424; LOC483954; PAI3; PAI-3; Pci; PCI-B; PLANH3; Plasma serine protease inhibitor; plasminogen activator inhibitor 3; plasminogen activator inhibitor III; plasminogen activator inhibitor-3; PROCI; Protein C inhibitor; serine (or cysteine) peptidase inhibitor, clade A, member 5; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serine (or cysteine) proteinase inhibitor, clade A, member 5; serpin A5; serpin B3; serpin family A member 5; serpin family B member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; serpin peptidase inhibitor, clade A, member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINA5; SERPINB3; SERPINB4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5104
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
• Gene Accession No.: P05154
• Gene Symbols: SERPINA5
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PAI3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG