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Invitrogen™ SERPINA7 Polyclonal Antibody
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Catalog No. PIPA5110353
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PIPA5110353 100 μL
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Catalog No. PIPA5110353 Supplier Invitrogen™ Supplier No. PA5110353
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Rabbit Polyclonal Antibody

Immunogen sequence: FLNDVKTLYE TEVFSTDFSN ISAAKQEINS HVEMQTKGKV VGLIQDLKPN TIMVLVNYIH FKAQWANPFD PSKTEDSSSF LIDKTTTVQV PMMHQMEQYY HLVDMELNCT VLQMDYSKNA LALFVLPKEG QMESVEAAMS SKTLKKWNRL LQKGWVDLFV PKFSISATYD LGATLLKMGI QHAYSENADF SGLTEDNGLK LSNAAHKAVL HIGEKGTEAA AVPEVELSDQ PENTFLHPII QIDRSFMLLI LERSTRSILF LGKVVNPTEA.

There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINA7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Serpina7
Gene Accession No. P05543, P35577, P61939
Gene Alias C730040N12Rik; RP1-82J11.2; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antipeptidase, antitrypsin), member 7; serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serine (or cysteine) proteinase inhibitor clade A (alpha-1 antiproteinase antitrypsin) member 7; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serpin A7; serpin family A member 7; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Serpina7; T4-binding globulin; TBG; thyroxin-binding globulin; thyroxine binding globulin; thyroxine-binding globulin
Gene Symbols Serpina7
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 331535, 6906, 81806
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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