Invitrogen™ SERPINB6 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518947

Catalog No. PIPA518947

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

The protein encoded by this gene is a member of the serpin superfamily, and ovalbumin-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: SERPINB6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINB6
• Gene Alias: 4930482L21Rik; CAP; Cytoplasmic antiproteinase; D330015H01Rik; DFNB91; DKFZp686I04222; MGC111370; MSTP057; ovalbumin; Peptidase inhibitor 6; PI6; PI-6; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); proteinase inhibitor 6; PTI; QtsA-17114; RP1-90J20.6; serine (or cysteine) peptidase inhibitor, clade B, member 6a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serine (or cysteine) proteinase inhibitor, clade B, member 6a; serine protease inhibitor 3; serine proteinase inhibitor B-43; Serpin B6; serpin family B member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Serpinb6; Serpinb6a; Spi3; thrombin inhibitor; unnamed protein product
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 5269
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35237
• Gene Symbols: SERPINB6
• Immunogen: Synthetic peptide sequence (NWDEQFDKENTEER) corresponding to the internal amino acids of SERPINB6 (aa 172-186).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG