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Invitrogen™ SERPINB6 Polyclonal Antibody
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Catalog No. PIPA582387
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100 μL
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PIPA582387 100 μL
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Catalog No. PIPA582387 Supplier Invitrogen™ Supplier No. PA582387
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FALNLLKTLG KDNSKNVFFS PMSMSCALAM VYMGAKGNTA AQMAQILSFN KSGGGGDIHQ GFQSLLTEVN KTGTQYLLRM ANRLFGEKSC DFLSSFRDSC QKFYQAEMEE LDFISAVEKS RKHINTWVAE KTEGKIAELL SPGSV Highest antigen sequence indentity to the following orthologs: Rat - 71%, Mouse - 75%.

The protein encoded by this gene is a member of the serpin superfamily, and ovalbumin-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINB6
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SERPINB6
Gene Accession No. P35237
Gene Alias 4930482L21Rik; CAP; Cytoplasmic antiproteinase; D330015H01Rik; DFNB91; DKFZp686I04222; MGC111370; MSTP057; ovalbumin; Peptidase inhibitor 6; PI6; PI-6; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); proteinase inhibitor 6; PTI; QtsA-17114; RP1-90J20.6; serine (or cysteine) peptidase inhibitor, clade B, member 6a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serine (or cysteine) proteinase inhibitor, clade B, member 6a; serine protease inhibitor 3; serine proteinase inhibitor B-43; Serpin B6; serpin family B member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Serpinb6; Serpinb6a; Spi3; thrombin inhibitor; unnamed protein product
Gene Symbols SERPINB6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SERPINB6. Recombinant protein control fragment (Product #RP-89218).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5269
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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