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Invitrogen™ SERPINB6 Polyclonal Antibody
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Catalog No. PIPA597301
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100 μL
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PIPA597301 100 μL
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Catalog No. PIPA597301 Supplier Invitrogen™ Supplier No. PA597301
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ENTEERLFKV SKNEEKPVQM MFKQSTFKKT YIGEIFTQIL VLPYVGKELN MIIMLPDETT DLRTVEKELT YEKFVEWTRL DMMDEEEVEV SLPRFKLEES YDMESVLRNL GMTDAFELGK A; Positive Samples: SW620, HeLa, HepG2, MCF7; Cellular Location: Cytoplasm.

The protein encoded by this gene is a member of the serpin superfamily, and ovalbumin-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINB6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SERPINB6
Gene Accession No. P35237, Q60854
Gene Alias 4930482L21Rik; CAP; Cytoplasmic antiproteinase; D330015H01Rik; DFNB91; DKFZp686I04222; MGC111370; MSTP057; ovalbumin; Peptidase inhibitor 6; PI6; PI-6; Placental thrombin inhibitor; protease inhibitor 6 (placental thrombin inhibitor); proteinase inhibitor 6; PTI; QtsA-17114; RP1-90J20.6; serine (or cysteine) peptidase inhibitor, clade B, member 6a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serine (or cysteine) proteinase inhibitor, clade B, member 6a; serine protease inhibitor 3; serine proteinase inhibitor B-43; Serpin B6; serpin family B member 6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; Serpinb6; Serpinb6a; Spi3; thrombin inhibitor; unnamed protein product
Gene Symbols SERPINB6, Serpinb6a
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SERPINB6 (NP_0045594).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20719, 291085, 5269
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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