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Invitrogen™ SERPINB9 Monoclonal Antibody (PI9-17)
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Catalog No. 01672076
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01-672-076 1 mL
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Catalog No. 01-672-076 Supplier Invitrogen™ Supplier No. MA135771
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Description

Mouse Monoclonal Antibody

The human intracellular serpin proteinase inhibitor 9 (PI9) is the only human protein able to inhibit the activity of the serine protease granzyme B. Granzyme B is expressed by cytotoxic lymphocytes and induces rapid target cell apoptosis. PI9-17 Mab was selected after immunization with full length recombinant PI9 produced in Escherichia coli. No cross reactivity with other, homologous serpins (PI6, PI8 and PAI-2) was observed.

PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995 [PubMed 8530382]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINB9
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone PI9-17
Concentration 250 μg/mL
Conjugate Unconjugated
Formulation Tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
Gene SERPINB9
Gene Accession No. P50453
Gene Alias BB283241; CAP3; CAP-3; Cytoplasmic antiproteinase 3; ovalbumin; peptidase inhibitor 9; PI9; PI-9; protease inhibitor 9 (ovalbumin type); serine (or cysteine) peptidase inhibitor, clade B, member 9; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9; serine (or cysteine) proteinase inhibitor, clade B, member 9; serine protease inhibitor 6; serpin B9; serpin family B member 9; serpin peptidase inhibitor, clade B (ovalbumin), member 9; serpin peptidase inhibitor, clade B, member 9; SERPINB9; Spi6; testicular tissue protein Li 180
Gene Symbols SERPINB9
Host Species Mouse
Immunogen Recombinant human full-lengthPI9 (proteinase inhibitor 9).
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5272
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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