Invitrogen™ SERPINC1 Monoclonal Antibody (15F2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA534939

Catalog No. PIMA534939

Description

Positive Control: HL-60 cell, HepG2 cell, SiHa cell, rat testis tissue, human lung carcinoma tissue, human liver tissue, human liver carcinoma tissue, mouse kidney tissue, HCT116 cell.

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Specifications

• Antigen: SERPINC1
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P01008
• Gene Symbols: Serpinc1
• Immunogen: Recombinant protein within Human SERPINC1 aa 150-370.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 15F2
• Conjugate: Unconjugated
• Gene: Serpinc1
• Gene Alias: AI114908; Antithrombin; Antithrombin 3; anti-thrombin 3; antithrombin III; antithrombin-III; AT3; At-3; AT3D; ATIII; hypothetical protein LOC540261; MGC22579; PRO0309; serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin family C member 1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1; Serpinc1; THPH7
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 462
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid