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Invitrogen™ SERPINC1 Polyclonal Antibody
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Catalog No. PIPA529646
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100 μL
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PIPA529646 100 μL
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Catalog No. PIPA529646 Supplier Invitrogen™ Supplier No. PA529646
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HCT116. Predicted reactivity: Human (92%), Mouse (87%), Rat (85%), Pig (86%), Sheep (85%), Rhesus Monkey (90%), Bovine (83%), Guinea pig (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SERPINC1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Serpinc1
Gene Accession No. P01008
Gene Alias AI114908; Antithrombin; Antithrombin 3; anti-thrombin 3; antithrombin III; antithrombin-III; AT3; At-3; AT3D; ATIII; hypothetical protein LOC540261; MGC22579; PRO0309; serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin family C member 1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1; Serpinc1; THPH7
Gene Symbols Serpinc1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Antithrombin III. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 462
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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