Invitrogen™ SERPINH1 Monoclonal Antibody (1C4-1A6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527711

Catalog No. PIMA527711

Description

1 μg/mL of MA5-27711 was sufficient for detection of HSP47 in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects 47kDa.

SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors, and its expression is induced by heat shock. The SERPINH1 protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to SERPINH1 have been found in patients with rheumatoid arthritis.

Specifications

• Antigen: SERPINH1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P19324, P50454
• Gene Symbols: SERPINH1
• Immunogen: Human HSP47, full length.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot, Immunocytochemistry
• Clone: 1C4-1A6
• Conjugate: Unconjugated
• Gene: SERPINH1
• Gene Alias: 47 kDa heat shock protein; arsenic-transactivated protein 3; AsTP 3; AsTP3; BERF-1; beta enolase repressor factor 1; CBP 1; CBP 2; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; collagen binding protein 1; collagen binding protein 2; collagen-binding protein; Colligen; Colligin; Colligin 1; Colligin 2; colligin-1; colligin-2; GP46; heat shock protein 47; HGNC 1547; Hsp 47; HSP47; J6; OI10; PIG 14; PIG14; PPROM; RA A47; RA-A47; rheumatoid arthritis antigen A-47; rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) peptidase inhibitor, clade H, member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); serine (or cysteine) proteinase inhibitor, clade H, member 1; serine protease inhibitor J6; serine proteinase inhibitor, clade H (heat shock protein 47), member 1; serpin family H member 1; serpin H1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serpin peptidase inhibitor, clade H, member 1; SERPINH1; SERPINH2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 12406, 871
• Content And Storage: -20°C
• Form: Liquid