Invitrogen™ Serum Amyloid P Monoclonal Antibody (273912)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523975

Catalog No. PIMA523975

Description

In Western blots, 100% cross-reactivity with recombinant human (rh) Pentraxin 2 and 25% cross-reactivity with recombinant mouse (rm) Pentraxin 2 is observed. In direct ELISAs, no cross-reactivity with rhPentraxin 2 or rmPentraxin 2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Specifications

• Antigen: Serum Amyloid P
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P23680
• Gene Symbols: APCS
• Immunogen: Mouse myeloma cell line NS0-derived recombinant rat Pentraxin2/SAP Gln21-Ser228 (predicted).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 273912
• Conjugate: Unconjugated
• Gene: APCS
• Gene Alias: 9.5S alpha-1-glycoprotein; amyloid P component, serum; APCS; APCS amyloid P-component serum protein; epididymis secretory sperm binding protein Li 92n; HEL-S-92n; MGC88159; Pentaxin related; pentaxin-related; Pentraxin 2; pentraxin-2; pentraxin-related; PTX 2; PTX2; SAMP; Sap; Serum amyloid P-component; Serum amyloid P-component(1-203)
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 29339
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized