Invitrogen™ Serum Amyloid P Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596028

Catalog No. PIPA596028

Description

Positive Samples: 293T Immunogen sequence: MNKPLLWISV LTSLLEAFAH TDLSGKVFVF PRESVTDHVN LITPLEKPLQ NFTLCFRAYS DLSRAYSLFS YNTQGRDNEL LVYKERVGEY SLYIGRHKVT SKVIEKFPAP VHICVSWESS SGIAEFWING TPLVKKGLRQ GYFVEAQPKI VLGQEQDSYG GKFDRSQSFV GEIGDLYMWD SVLPPENILS AYQGTPLPAN ILDWQALNYE IRGYVIIKPL VWV.

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Specifications

• Antigen: Serum Amyloid P
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APCS
• Gene Alias: 9.5S alpha-1-glycoprotein; amyloid P component, serum; APCS; APCS amyloid P-component serum protein; epididymis secretory sperm binding protein Li 92n; HEL-S-92n; MGC88159; Pentaxin related; pentaxin-related; Pentraxin 2; pentraxin-2; pentraxin-related; PTX 2; PTX2; SAMP; Sap; Serum amyloid P-component; Serum amyloid P-component(1-203)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20219, 29339, 325
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.65 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P02743, P12246, P23680
• Gene Symbols: APCS
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-223 of human APCS (NP_0016301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov