Invitrogen™ SESN1 Recombinant Rabbit Monoclonal Antibody (HL1750)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547167

Catalog No. PIMA547167

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: SESN1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q9Y6P5
• Gene Symbols: Sesn1
• Immunogen: Recombinant fragment of human SESN1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL1750
• Conjugate: Unconjugated
• Gene: Sesn1
• Gene Alias: 1110002G11Rik; AU044290; LOW QUALITY PROTEIN: sestrin-1; p53 activated gene 26; p53 regulated PA26 nuclear protein; p53-regulated protein PA26; PA26; Sesn1; Sest1; sestrin 1; sestrin-1; si:ch211-51a19.4; WITHDRAWN: zgc:103669; zgc:103669; zgc:91970
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 27244
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov