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Invitrogen™ SESN1 Polyclonal Antibody
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Catalog No. PIPA5101880
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100 μL
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PIPA5101880 100 μL
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Catalog No. PIPA5101880 Supplier Invitrogen™ Supplier No. PA5101880
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SESN1.

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SESN1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Sesn1
Gene Accession No. P58006, Q9Y6P5
Gene Alias 1110002G11Rik; AU044290; LOW QUALITY PROTEIN: sestrin-1; p53 activated gene 26; p53 regulated PA26 nuclear protein; p53-regulated protein PA26; PA26; Sesn1; Sest1; sestrin 1; sestrin-1; si:ch211-51a19.4; WITHDRAWN: zgc:103669; zgc:103669; zgc:91970
Gene Symbols Sesn1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SESN1(Accession Q9Y6P5), corresponding to amino acid residues R127-L177.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140742, 27244, 294518
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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