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Invitrogen™ SESN1 Polyclonal Antibody
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Catalog No. PIPA570072
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100 μL
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PIPA570072 100 μL
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Catalog No. PIPA570072 Supplier Invitrogen™ Supplier No. PA570072
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SESN1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Sesn1
Gene Accession No. 0
Gene Alias 1110002G11Rik; AU044290; LOW QUALITY PROTEIN: sestrin-1; p53 activated gene 26; p53 regulated PA26 nuclear protein; p53-regulated protein PA26; PA26; Sesn1; Sest1; sestrin 1; sestrin-1; si:ch211-51a19.4; WITHDRAWN: zgc:103669; zgc:103669; zgc:91970
Gene Symbols Sesn1
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human SESN1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 294518
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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