Invitrogen™ SESN1 Recombinant Rabbit Monoclonal Antibody (7I5Y4)

Catalog No.	Quantity
PIMA538000	100 μL

Catalog No. PIMA538000 Supplier Invitrogen™ Supplier No. MA538000

Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HepG2, PC-3 Immunogen sequence: KTQHYLLQMD GPLPLHYRHY IGIMAAARHQ CSYLVNLHVN DFLHVGGDPK WLNGLENAPQ KLQNLGELNK VLAHRPWLIT KEHIEGLLKA EEHSWSLAEL V.

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: SESN1
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: 7I5Y4
• Concentration: 0.83 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Sesn1
• Gene Accession No.: P58006, Q9Y6P5
• Gene Alias: 1110002G11Rik; AU044290; LOW QUALITY PROTEIN: sestrin-1; p53 activated gene 26; p53 regulated PA26 nuclear protein; p53-regulated protein PA26; PA26; Sesn1; Sest1; sestrin 1; sestrin-1; si:ch211-51a19.4; WITHDRAWN: zgc:103669; zgc:103669; zgc:91970
• Gene Symbols: Sesn1
• Host Species: Rabbit
• Immunogen: Synthetic peptide
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 140742, 27244
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG