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Invitrogen™ SESN3 Polyclonal Antibody
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Catalog No. PIPA592350
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100 μL
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PIPA592350 100 μL
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Catalog No. PIPA592350 Supplier Invitrogen™ Supplier No. PA592350
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP; Positive Samples: HeLa, A-549.

May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SESN3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SESN3
Gene Accession No. P58005
Gene Alias 5630400E15Rik; BC003348; Sesn3; SEST3; sestrin 3; sestrin-3
Gene Symbols SESN3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_6532662).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 143686
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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