Invitrogen™ SETDB2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518112

Catalog No. PIPA518112

Description

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1,000.

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).

Specifications

• Antigen: SETDB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SETDB2
• Gene Alias: bifurcated 2; C13orf4; Chronic lymphocytic leukemia deletion region gene 8 protein; Clld8; CLLL8; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Gm293; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; Setdb2; Setdb2-Phf11-1-Phf11-2 fusion
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 83852
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q96T68
• Gene Symbols: SETDB2
• Immunogen: Synthetic peptide sequence (GEKNGDAKTFWME) corresponding to the N-terminus amino acids of SETDB2 (aa 2-15).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG