Invitrogen™ SETDB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530848

Catalog No. PIPA530848

Description

Recommended positive controls: SK-N-SH. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).

Specifications

• Antigen: SETDB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SETDB2
• Gene Alias: bifurcated 2; C13orf4; Chronic lymphocytic leukemia deletion region gene 8 protein; Clld8; CLLL8; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Gm293; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; Setdb2; Setdb2-Phf11-1-Phf11-2 fusion
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96T68
• Gene Symbols: SETDB2
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human SETDB2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG