Invitrogen™ SETDB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110357

Catalog No. PIPA5110357

Description

Immunogen sequence: SGACLMKMPL NLKGENPLQL PIKCHFQRRH AKTNSHSSAL HVSYKTPCGR SLRNVEEVFR YLLETECNFL FTDNFSFNTY VQLARNYPKQ KEVVSDVDIS NGVESVPISF CNEIDSRKLP QFKYRKTVWP RAYNLTNFSS MFTDSCDCSE GCIDITKCAC LQLTARNAKT SPLSSDKITT GYKYKRLQRQ IPTGIYECSL LCKCNRQLCQ NRVVQHGPQV RLQVFKTEQK G.

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).

Specifications

• Antigen: SETDB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SETDB2
• Gene Alias: bifurcated 2; C13orf4; Chronic lymphocytic leukemia deletion region gene 8 protein; Clld8; CLLL8; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Gm293; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; Setdb2; Setdb2-Phf11-1-Phf11-2 fusion
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100361710, 239122
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.04 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q8C267
• Gene Symbols: SETDB2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 148-378 of human SETDB2 (NP_1141212).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov