Setdb2 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 200401N99S

Catalog No. 50-199-0930

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This Protein A purified antibody is directed against mouse Setdb2. Expect reactivity with Setdb2 from mouse and human sources. Reactivity against homologues from other sources is not known.

Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).

Specifications

• Antigen: Setdb2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SETDB2
• Gene Alias: bifurcated 2; C13orf4; Chronic lymphocytic leukemia deletion region gene 8 protein; CLLD8; CLLL8; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Gm293; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; SETDB2; Setdb2-Phf11-1-Phf11-2 fusion
• Host Species: Rabbit
• Quantity: 25 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody

• Applications: ELISA, Western Blot
• Concentration: 0.98 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q8C267, Q96T68
• Gene Symbols: SETDB2
• Immunogen: Setdb2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a full length protein corresponding to mouse Setdb2.
• Regulatory Status: RUO
• Gene ID (Entrez): 239122, 83852
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid