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Invitrogen™ SF1 Polyclonal Antibody
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Catalog No. PIPA553871
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100 μL
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PIPA553871 100 μL
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Catalog No. PIPA553871 Supplier Invitrogen™ Supplier No. PA553871
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NQDTMEQKTV IPGMPTVIPP GLTREQERAY IVQLQIEDLT RKLRTGDLGI PPNPEDRSPS PEPIYNSEGK RLNTREFRTR KKLEEERHNL ITEMVALNPD FKPPADYKPP ATRVSDKVMI PQDEYPEINF VGLLI Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Splicing factor 1 is a nuclear pre-mRNA splicing factor. The protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SF1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SF1
Gene Accession No. Q15637
Gene Alias BBP; D11S636; M ZFM1; Mammalian branch point-binding protein; MBBP; MZFM; SF; SF1; Splicing factor 1; transcription factor ZFM1; WBP4; wu:fc09f06; ZCCHC25; ZFM1; Zfp162; Zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162
Gene Symbols SF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SF1. Recombinant protein control fragment (Product #RP-100742).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7536
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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