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Invitrogen™ SF3B1 Recombinant Rabbit Monoclonal Antibody (JB40-32)
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Catalog No. PIMA534649
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PIMA534649 100 μL
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Catalog No. PIMA534649 Supplier Invitrogen™ Supplier No. MA534649
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Mouse thymus tissue lysate, Hela, human colon cancer tissue, human skin tissue, human kidney tissue, mouse small intestine tissue.

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex. The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SF3B1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JB40-32
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene SF3B1
Gene Accession No. O75533
Gene Alias 155kDa; 2810001M05Rik; AA409119; Hsh155; LOW QUALITY PROTEIN: splicing factor 3B subunit 1; MDS; pre-mRNA processing 10; pre-mRNA splicing factor SF3b, 155 kDa subunit; pre-mRNA-splicing factor SF3b 155 kDa subunit; PRP10; PRPF10; SAP 155; SAP155; SF3B1; SF3b155; spliceosome-associated protein 155; Splicing factor 3B subunit 1; splicing factor 3b subunit 1, 155kDa; splicing factor 3b, subunit 1; splicing factor 3b, subunit 1, 155 kDa; splicing factor 3b, subunit 1, 155kD; splicing factor 3b, subunit 1, 155kDa; TA-8; Targ4; transforming growth factor alpha regulated gene 4; tst; wu:fb99f09
Gene Symbols SF3B1
Host Species Rabbit
Immunogen Recombinant protein within Human SF3B1 aa 1-105.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23451
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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