Invitrogen™ SF3B14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588980

Catalog No. PIPA588980

Description

Immunogen sequence: MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV GNTPETRGTA YVVYEDIFDA KNACDHLSGF NVCNRYLVVL YYNANRAFQK MDTKKKEEQL KLLKEKYGIN TDPPK; Positive Samples: K-562, HeLa, Mouse spleen; Cellular Location: Nucleus.

SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Specifications

• Antigen: SF3B14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SF3B6
• Gene Alias: 0610009D07Rik; 6030419K15Rik; AV001342; CGI-110; HSPC175; Ht006; P14; pre mRNA branch site protein p14; pre-mRNA branch site protein p14; SAP14; SAP14a; SF3b 14 kDa subunit; Sf3b14; SF3B14a; SF3B6; spliceosome-associated protein, 14 kDa subunit; spliceosome-associated protein, 14-kDa; Splicing factor 3B subunit 6; splicing factor 3B, 14 kDa subunit; splicing factor 3B, 14 kDa subunit-like; splicing factor 3B, subunit 6; splicing factor 3b, subunit 6, 14kDa
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51639, 66055
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P59708, Q9Y3B4
• Gene Symbols: SF3B6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human SF3B6 (NP_0571311).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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