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Invitrogen™ SF3B2 Polyclonal Antibody
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Catalog No. PIPA596456
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100 μL
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PIPA596456 100 μL
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Catalog No. PIPA596456 Supplier Invitrogen™ Supplier No. PA596456
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SLGMPVGPNA HKVPPPWLIA MQRYGPPPSY PNLKIPGLNS PIPESCSFGY HAGGWGKPPV DETGKPLYGD VFGTNAAEFQ TKTEEEEIDR TPWGELEPSD EESSEEEEEE ESDEDKPDET GFITPADSGL ITPGGFSSVP AGMETPELIE LRKKKIEEAM DGSETPQLFT VLPEKRTATV GGAMMGSTHI YDMSTVMSRK GPAPELQGVE VALAPEELEL DPMAMTQKYE EHVREQQAQV EKEDFSDMVA EHAAKQKQKK RKAQPQDSRG GSKKYKEFKF; Positive Samples: HeLa, MCF7, SW620, A375, Mouse testis; Cellular Location: Nucleus.

Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SF3B2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SF3B2
Gene Accession No. Q13435
Gene Alias 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; Cus1; pre-mRNA splicing factor SF3b 145 kDa subunit; pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SAP145; SF3b1; SF3B145; SF3b150; SF3B2; spliceosome associated protein 145; spliceosome-associated protein 145; Splicing factor 3B subunit 2; splicing factor 3b, subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
Gene Symbols SF3B2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 616-895 of human SF3B2 (NP_0068332).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10992, 293671, 319322
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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