SF3B2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548739

Catalog No. PA548739

Description

Subunit of the splicing factor SF3B required for  ft.A ft. complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the  ft.E ft. complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Specifications

• Antigen: SF3B2
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q13435
• Gene Alias: Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 400 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 10992, 293671, 319322

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: SF3B2
• Format: Liquid
• Gene Symbols: SF3B2
• Immunogen: KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human SF3B2.
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse, Rat