Invitrogen™ SF3B4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5111585	Invitrogen™ PA5111585	100 μL

Description

Immunogen sequence: VSYAFKKDSK GERHGSAAER LLAAQNPLSQ ADRPHQLFAD APPPPSAPNP.

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Specifications

• Antigen: SF3B4
• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15427
• Gene ID (Entrez): 10262
• Immunogen: Recombinant Protein corresonding to Human SF3B4. Recombinant protein control fragment (Product #RP-105328).
• Product Type: Antibody

• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: Sf3b4
• Gene Alias: 49kD; AFD1; chunp6902; fb36a04; Hsh49; MGC10828; pre-mRNA-splicing factor SF3b 49 kDa subunit; SAP 49; Sap49; SAP49MGC10828; sf3b4; SF3b49; SF3b50; spliceosomal protein; spliceosome-associated protein (U2 snRNP); spliceosome-associated protein 49; Splicing factor 3B subunit 4; splicing factor 3b, subunit 4; splicing factor 3b, subunit 4, 49kD; splicing factor 3b, subunit 4, 49kDa; Unknown (protein for IMAGE:8120437); wu:fb36a04
• Gene Symbols: Sf3b4
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography