Invitrogen™ SF3B4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531056

Catalog No. PIPA531056

Description

Recommended positive controls: 293T, A431, Jurkat, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (96%), Xenopus laevis (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Specifications

• Antigen: SF3B4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sf3b4
• Gene Alias: 49kD; AFD1; chunp6902; fb36a04; Hsh49; MGC10828; pre-mRNA-splicing factor SF3b 49 kDa subunit; SAP 49; Sap49; SAP49MGC10828; sf3b4; SF3b49; SF3b50; spliceosomal protein; spliceosome-associated protein (U2 snRNP); spliceosome-associated protein 49; Splicing factor 3B subunit 4; splicing factor 3b, subunit 4; splicing factor 3b, subunit 4, 49kD; splicing factor 3b, subunit 4, 49kDa; Unknown (protein for IMAGE:8120437); wu:fb36a04
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10262, 107701
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.92 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q15427, Q8QZY9
• Gene Symbols: Sf3b4
• Immunogen: Recombinant fragment corresponding to a region within amino acids 37 and 258 of Human SF3B4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG