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Invitrogen™ SF3B4 Polyclonal Antibody
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Catalog No. PIPA531056
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100 μL
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PIPA531056 100 μL
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Catalog No. PIPA531056 Supplier Invitrogen™ Supplier No. PA531056
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (96%), Xenopus laevis (99%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SF3B4
Applications Western Blot
Classification Polyclonal
Concentration 0.92 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Sf3b4
Gene Accession No. Q15427, Q8QZY9
Gene Alias 49kD; AFD1; chunp6902; fb36a04; Hsh49; MGC10828; pre-mRNA-splicing factor SF3b 49 kDa subunit; SAP 49; Sap49; SAP49MGC10828; sf3b4; SF3b49; SF3b50; spliceosomal protein; spliceosome-associated protein (U2 snRNP); spliceosome-associated protein 49; Splicing factor 3B subunit 4; splicing factor 3b, subunit 4; splicing factor 3b, subunit 4, 49kD; splicing factor 3b, subunit 4, 49kDa; Unknown (protein for IMAGE:8120437); wu:fb36a04
Gene Symbols Sf3b4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SF3B4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10262, 107701
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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