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Invitrogen™ sfl Polyclonal Antibody
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Catalog No. FEPA5144403
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100 μL
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FEPA5144403 100 μL
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Catalog No. FEPA5144403 Supplier Invitrogen™ Supplier No. PA5144403
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Description

Rabbit Polyclonal Antibody

sfl Polyclonal Antibody for Western Blot, ELISA

Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in diffusion of morphogen wingless (wg) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of wg morphogens. Required for wg signaling during both embryonic and imaginal disk development. Also required for FGF receptor signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen sfl
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.032 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene sfl
Gene Accession No. Q9V3L1
Gene Alias Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase
Gene Symbols sfl
Host Species Rabbit
Immunogen Recombinant Drosophila melanogaster (Fruit fly) NDST protein (1-172aa).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 38736
Target Species Drosophila
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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