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SFPQ Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 155851AP150UL

Encompass_Preferred

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Catalog No. 50-173-0330


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Description

Description

SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer′s disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types.
Specifications

Specifications

SFPQ
Polyclonal
Unconjugated
SFPQ
100 kDa DNA pairing protein, hPOMp100, POMP100, PSF, PTB associated splicing factor, SFPQ
Rabbit
Antigen Affinity Chromatography
RUO
252855, 6421, 71514
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P23246, Q8VIJ6
SFPQ
SFPQ Fusion Protein Ag7181
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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